What Does L-Leucine Supplement Do For The Body?

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What Does L-Leucine Supplement Do

Leucine is a branched-chain amino acid that is required by the body, and because of this, it is good to take it as an L-leucine supplement. Unfortunately, this amino acid is not produced by our bodies. As a result, we must approach it via the foods we consume or supplements we intake. Leucine has several advantages. Many of the items in your kitchen may contain leucine. For example, it is found in protein-rich diets.

This amino acid is required for muscular strength to be maintained. It also benefits skin health. L-leucine is also suitable for weight reduction, diabetic control, and heart disease prevention. Leucine supplementation is becoming a health-conscious buzzword. So, let’s look into how leucine may help us and why it is good to take an L-leucine supplement.

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TABLE OF CONTENTS:

  1. Essential Acids and Their Benefits
  2. What Is L-leucine?
  3. Recommended Daily Intake of L-Leucine
  4. L-Leucine Deficiency
  5. L-leucine Benefits
  6. Foods Rich in L-Leucine
  7. L-Leucine Supplementation
  8. Benefits of L-Leucine Supplements in Exercise
  9. L-Leucine Overdose
  10. Possible Side-effects of L-Leucine

Essential Acids and Their Benefits

Before starting with the fundamental question, “What does L-leucine do?” we must know what amino acids are.

Amino acids compose proteins, the building blocks of the body. They are necessary for muscle growth and provide additional advantages. Our bodies need 20 amino acids to operate appropriately. We can produce some of them. They are referred to as non-essential amino acids. Others, however, cannot be made by the body. They are also known as essential amino acids. As a result, you must get them from a well-balanced and nutritious diet. Egg, meat, and dairy products are examples of foods that contain essential amino acids.

There are 9 essential and 11 non-essential amino acids. These amino acids are very beneficial to our health. However, lacking amino acids leads to poor immunity, digestive difficulties, mental disease, depression, and reproductive issues. As a result, keeping track of amino acid consumption is critical. A diet high in amino acids may help avoid an essential amino acid deficit.

What Is L-leucine?

L-leucine is an essential amino acid with a branch chain. According to research, it helps in the regulation of blood sugar levels. Leucine also aids in wound healing. Furthermore, it enhances growth hormone secretion. Leucine also improves the appearance of the skin. In general, it is essential for the development and function of bones and muscles. Eggs, fish, milk, and meat are all rich sources of L-leucine.

The following is an estimate of the protein consumption of a sedentary adult:  

  • Men: 56 grams per day;
  • Women: 46 grams per day.

However, additional factors like lifestyle, health, lifespan, dietary limitations, and food tolerance must be considered. It provides around 30% of the daily calorie requirement. According to one research, individuals’ daily leucine need is 39mg/kg. However, the research implied that the demand would be more significant for young people and children in their developing periods.  

L-Leucine Deficiency

Leucine deficiency impairs the function of the muscles and the liver. The body becomes very weary as a result of a lack of leucine. Specific symptoms of leucine insufficiency may occur. Among these signs are:

  • Fatigue;
  • Poor wound healing;
  • Poor muscle gain;
  • Weight gain.

People suffering from eating disorders such as bulimia and anorexia nervosa are prone to leucine deficiency. In addition, an imbalanced diet might result in leucine insufficiency. For example, it may be caused by eating too many fast meals and not getting enough protein. Furthermore, people who are under strain and experience emotional stress due to long working hours may need extra leucine. So that is why these people should intake an l-leucine supplement. Some lifestyle factors might also result in a deficit.

According to research, intensive aerobic exercise and weight training may increase the daily intake of L-leucine. There are proposals to raise the existing recommended daily dose of L-leucine in sedentary people from 14mg/kg body weight to 45mg/kg body weight. Individuals who engage in intense physical activity and strength training should see an increase in protein synthesis. Otherwise, it will have an impact on their muscular strength and performance. Furthermore, patients with liver diseases are predisposed to leucine deficiency. As a result, persons in these groups need an L-leucine supplement. To summarize, L-leucine aids in tissue regeneration, wound healing, muscle building, and muscle repair and loss prevention.   

L-leucine Benefits

Knowing the l-leucine function, I’ll go through its advantages in our bodies. This way, you’ll know when you may take it as a supplement and how it will benefit your health.

Controls Blood Glucose Levels

Leucine benefits diabetics by increasing insulin output. It happens when you obtain it from your food. Furthermore, evidence shows that leucine regulates blood sugar levels.

Helps in Growth and Development

Children need L-leucine throughout their developing years because it stimulates the production of particular growth hormones. Furthermore, protein-rich diets provide enough levels of L-leucine. As a result, it is critical to supplement a child’s diet with leucine-rich foods such as eggs, lentils, sesame seeds, chickpeas, and soybeans in forms such as tofu, tempeh, edamame, brown rice, and nuts. You can also take an L-leucine supplement and add it to your kid’s diet.

L-Leucine Aids in Muscle Building

L-leucine is required by our bodies for bone health. It also boosts muscular development and strength. Bodybuilding is one of the most common uses for branched amino acids. These acids degrade during protein synthesis, stimulating muscular development. Aside from muscle growth, L-leucine offers many additional advantages for athletes.

According to research, they slow the process of muscle deterioration. It is common among athletes and anybody who engages in strenuous physical activity. Aside from muscle growth, L-leucine aids in the repair of systems. It helps prevent injury and muscle loss in older persons with sarcopenia.  

Aids in Weight Loss

L-leucine also aids with weight control. It helps to reduce food cravings by providing a sense of fullness. Furthermore, research suggests that the L-leucine supplement boosts the response to the hormone leptin, which is involved in hunger control. L-leucine also reduces muscle loss after weight reduction. On the contrary, it maintains muscular mass while decreasing fat. Furthermore, they prevent blood sugar increases.

Improves Skin Health

L-leucine is beneficial to the skin since it contains anti-aging qualities. It smoothes out wrinkles and fine lines. Muscle weakening and sagging accompany aging skin. As a result, food consumption and leucine-based treatments limit skin aging. Finally, the skin is firmer, smoother, and healthier.

Foods Rich in L-Leucine

Because assimilation and absorption are constantly improved by food sources, adding nutrients to meals is always the best option. Furthermore, dietary sources are more convenient and, in some cases, less expensive than supplements. Supplements are appropriate for specific requirements. They, on the other hand, may have adverse side effects.

An L-leucine supplement should combine valine, isoleucine, and other branched-chain amino acids. You may prevent them by including them in your diet. Protein and amino acid concentrations are often unknown. It is one of the causes of a lack of necessary amino acids. Such information is lacking even on food packaging nutrition labels. As a result, knowing where to get L-leucine is critical.

Meat Sources

Protein is abundant in non-vegetarian meals. As a result, chicken, hog, steak, tuna fish, and salmon fish are high in L-leucine. These meat sources provide around 60% of the daily leucine requirement. Steak is the most nutritious meat, providing 90% of this amino acid. However, since red meat contains a lot of saturated fat and salt, you should eat it in moderation. Excessive consumption of red meat may result in several health issues.

Eggs

Eggs are nutritious since they include various elements such as proteins, vitamins, and minerals. A giant egg contains around 0.5 grams of L-leucine. Eggs are a protein-rich meal essential for everyone, including bodybuilders and strength athletes. Furthermore, studies show that including whole eggs may aid in muscle building. As a result, it is a lifesaver for gym rats.  

Oats

Oatmeal is well-known as a breakfast cereal. It is popular in various forms, including overnight smoothies and granola bars. Furthermore, oats are beneficial for weight loss. That is because one cup of oats contains 0.5 grams of L-leucine, which benefits heart health. Moreover, research indicates that oats are a good source of B-glucan. This component aids with cholesterol regulation.  

Lentils

Lentils are a legume high in fiber, protein, and antioxidants. One cup of lentils contains 1.3 grams of leucine and is high in fiber. Lentils also include probiotics, which help maintain a healthy gut microbiome. They may be used in soups and curries to create nutritious food for yourself and your children.

Pea Beans

Pea beans have high L-leucine content and are also known as navy beans. They are most often seen in tinned or soup form. Leucine is present in 0.7 grams per 100 grams of these beans. Other minerals in pea beans include vitamin B, iron, magnesium, and manganese. Navy beans are high in fiber and low in saturated fat. According to research, these beans may help you lose weight. It also aids in regulating blood sugar, cholesterol, and blood pressure.  

Cottage Cheese

Cottage cheese, often known as paneer, is a high-protein vegetarian option. 100 grams of cottage cheese, for example, has around 1.27 grams of L-leucine. Cottage cheese is a good source of protein for vegetarians, as well as calcium, selenium, phosphorus, and vitamins. Furthermore, research shows that cottage cheese provides a sensation of fullness. As a result, they aid in weight reduction.

Peanuts

Peanuts are high in a variety of nutrients. Furthermore, peanuts are rich in protein and healthy fats. L-leucine is found in around 28 grams of peanuts. Moreover, peanuts aid in blood pressure regulation and are a rich source of cholesterol. As a result, eat a handful of peanuts as a snack to get the most advantages. If your goal is to lose weight, I suggest consulting a nutritionist about how much peanuts benefit you.  

Seeds

Apart from being a good source of L-leucine, sesame, pumpkin, and hemp seeds benefit your health. These seeds may be used in salads, smoothies, desserts, and pasta. Sesame seeds are also high in vitamin B and fiber. They also contain significant quantities of minerals such as calcium, zinc, and manganese. According to research, these seeds improve blood sugar levels. Pumpkin seeds are also abundant in fiber, unsaturated fatty acids, iron, and zinc.

Spirulina

Spirulina is a kind of blue-green algae that thrives in bodies of water. Some of them are edible. They have several health advantages. Spirulina is high in antioxidants and helps to minimize oxidative stress produced by free radicals. Spirulina contains anti-inflammatory L-leucine, and it helps with muscle repair. The powder may be used in smoothies or liquids. One scoop of spirulina contains roughly 350 grams of L-leucine.  

L-Leucine Supplementation

Antinutrients are found in a variety of foods. These inhibit L-leucine absorption from the diet. In the case of supplements, however, this is not an issue. They are available in powder and pill form. Supplements are immediately and readily absorbed.

2-5 grams of L-leucine supplement is advised. To maximize effectiveness, combine it with other amino acids such as valine and isoleucine. It is best to take the L-leucine supplement on an empty stomach. You may, however, drink it at any time of day. Consult a nutritionist or a healthcare expert for instructions on how to use it.  

Benefits of L-Leucine Supplements in Exercise

  • The L-leucine supplement enhances muscular activation when given 30 minutes before an exercise. As a result, it aids in bodybuilding and endurance training. It also helps with fat reduction without causing muscle loss.
  • The L-leucine supplement boosts protein synthesis when consumed after an exercise. Leucine may also be added to protein drinks. It promotes muscular growth.
  • An L-leucine supplement is a useful energy source if consumed between workouts. It also slows the degradation of proteins.
  • The L-leucine supplement is a beneficial addition to your diet.
  • Its use before night promotes muscle repair after exercise.

L-Leucine Overdose

Excess leucine in the body is referred to as leucine overdose. This is an unusual instance. Overdoes of leucine do not arise as a result of food consumption. However, the L-leucine supplement makes it feasible. Athletes and bodybuilders often ingest excessive amounts of an L-leucine supplement. L-leucine supplement overdose symptoms include:  

  • Nausea;
  • Stomach pain;
  • Diarrhea;
  • Indigestion.

According to research, the tolerated maximum limit for L-leucine supplement is 500 mg daily. Еxceeding this limit is not recommended.

Possible Side-effects of L-Leucine

You should know the potential adverse effects of using an L-leucine supplement. Let’s see which they are.

Metabolic Changes

Excessive use of amino acids might be harmful. It throws off the nitrogen balance and affects metabolism. Furthermore, it disrupts various bodily systems. According to research, it influences eating habits and food consumption.

Hypoglycemia

Controlling blood glucose levels is one of leucine’s applications. However, if supplementation levels rise, hypoglycemia might occur. Low blood sugar levels are typical for patients suffering from this. In the worst-case scenario, the person may go unconscious. Before including an L-leucine supplement in your diet, consult your doctor and a dietician.

Summary

Because their function is as significant as other nutrients, essential amino acids are critical in supporting human health. L-leucine is effective in a variety of medical disorders. As a result, leucine has become a buzzword among the health-conscious. It is essential for muscle growth and repair. Even though leucine insufficiency is uncommon, you should keep track of your intake. Eggs, oats, lentils, and seeds are all high in leucine.

Many people who are interested in physical fitness use an L-leucine supplement. However, before using it, you should always visit a medical nutritionist to prevent potential adverse effects. Furthermore, dietary sources of L-leucine may be the best choice.

References:

  1. Komar, B., Schwingshackl, L., & Hoffmann, G. (2015). Effects of leucine-rich protein supplements on anthropometric parameter and muscle strength in the elderly: a systematic review and meta-analysis. The journal of nutrition, health & aging, 19(4), 437–446. https://doi.org/10.1007/s12603-014-0559-4
  2. Papadopoulou S. K. (2020). Rehabilitation Nutrition for Injury Recovery of Athletes: The Role of Macronutrient Intake. Nutrients, 12(8), 2449. https://doi.org/10.3390/nu12082449
  3. Kalogeropoulou, D., Lafave, L., Schweim, K., Gannon, M. C., & Nuttall, F. Q. (2008). Leucine, when ingested with glucose, synergistically stimulates insulin secretion and lowers blood glucose. Metabolism: clinical and experimental, 57(12), 1747–1752. https://doi.org/10.1016/j.metabol.2008.09.001
  4. Yang, J., Chi, Y., Burkhardt, B. R., Guan, Y., & Wolf, B. A. (2010). Leucine metabolism in regulation of insulin secretion from pancreatic beta cells. Nutrition reviews, 68(5), 270–279. https://doi.org/10.1111/j.1753-4887.2010.00282.x
  5. National Research Council (US) Subcommittee on the Tenth Edition of the Recommended Dietary Allowances. Recommended Dietary Allowances: 10th Edition. Washington (DC): National Academies Press (US); 1989. 6, Protein and Amino Acids. Available from: https://www.ncbi.nlm.nih.gov/books/NBK234922/
  6. Anura V. Kurpad, Meredith M. Regan, Tony Raj, Justin V. Gnanou, Branched-Chain Amino Acid Requirements in Healthy Adult Human Subjects, The Journal of Nutrition, Volume 136, Issue 1, January 2006, Pages 256S–263S, https://doi.org/10.1093/jn/136.1.256S
  7. Mobley CB, Haun CT, Roberson PA, Mumford PW, Romero MA, Kephart WC, Anderson RG, Vann CG, Osburn SC, Pledge CD, Martin JS, Young KC, Goodlett MD, Pascoe DD, Lockwood CM, Roberts MD. Effects of Whey, Soy or Leucine Supplementation with 12 Weeks of Resistance Training on Strength, Body Composition, and Skeletal Muscle and Adipose Tissue Histological Attributes in College-Aged Males. Nutrients. 2017; 9(9):972. https://doi.org/10.3390/nu9090972
  8. Pedroso, J. A., Zampieri, T. T., & Donato, J., Jr (2015). Reviewing the Effects of L-Leucine Supplementation in the Regulation of Food Intake, Energy Balance, and Glucose Homeostasis. Nutrients, 7(5), 3914–3937. https://doi.org/10.3390/nu7053914
  9. Mero A. (1999). Leucine supplementation and intensive training. Sports medicine (Auckland, N.Z.), 27(6), 347–358. https://doi.org/10.2165/00007256-199927060-00001
  10. Casperson, S. L., Sheffield-Moore, M., Hewlings, S. J., & Paddon-Jones, D. (2012). Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein. Clinical nutrition (Edinburgh, Scotland), 31(4), 512–519. https://doi.org/10.1016/j.clnu.2012.01.005
  11. Newmire, D. E., Rivas, E., Deemer, S. E., Willoughby, D. S., & Ben-Ezra, V. (2019). The Impact of a Large Bolus Dose of l-leucine and l-isoleucine on Enteroendocrine and Pancreatic Hormones, and Glycemia in Healthy, Inactive Adults. Nutrients, 11(11), 2650. https://doi.org/10.3390/nu11112650
  12. Zampieri, T. T., Torres-Leal, F. L., Campaña, A. B., Lima, F. B., & Donato, J., Jr (2014). L-leucine supplementation worsens the adiposity of already obese rats by promoting a hypothalamic pattern of gene expression that favors fat accumulation. Nutrients, 6(4), 1364–1373. https://doi.org/10.3390/nu6041364
  13. Borack, M. S., & Volpi, E. (2016). Efficacy and Safety of Leucine Supplementation in the Elderly. The Journal of nutrition, 146(12), 2625S–2629S. https://doi.org/10.3945/jn.116.230771
  14. Zanchi, N. E., Guimarães-Ferreira, L., de Siqueira-Filho, M. A., Felitti, V., Nicastro, H., Bueno, C., Lira, F. S., Naimo, M. A., Campos-Ferraz, P., Nunes, M. T., Seelaender, M., de Oliveira Carvalho, C. R., Blachier, F., & Lancha, A. H. (2012). Dose and latency effects of leucine supplementation in modulating glucose homeostasis: opposite effects in healthy and glucocorticoid-induced insulin-resistance states. Nutrients, 4(12), 1851–1867. https://doi.org/10.3390/nu4121851
  15. Takegaki, J., Sase, K., Yasuda, J., Shindo, D., Kato, H., Toyoda, S., Yamada, T., Shinohara, Y., & Fujita, S. (2020). The Effect of Leucine-Enriched Essential Amino Acid Supplementation on Anabolic and Catabolic Signaling in Human Skeletal Muscle after Acute Resistance Exercise: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Trial. Nutrients, 12(8), 2421. https://doi.org/10.3390/nu12082421

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